Giant Condyloma Accuminata in Pregnancy, Use of Trichloroacetic Acid combined with electrocauterization and excision Procedure: A Case Report

Putri Cinthya Ismihari, Riyana Noor Oktaviyanti


Condyloma acuminata is a sexually transmitted disease caused by the Human Papilloma Virus (HPV). During pregnancy, condyloma acuminata can proliferate rapidly due to changes in immunity and increased blood supply. One of the safest therapeutic modalities is trichloroacetic acid (TCA). Electrocautery is another modality in pregnant patients.  A 16-year-old woman, 6-months pregnant, complained of a wart-like lump in the pubic area getting more prominent since the last two weeks and covering the vagina surface. The lump is not itchy and painless. From history-taking it was found that patient often changes partners. On physical examination, the lesions were multiple papules with a verrucous surface. The results of the work-up showed a positive acetowhite test. Patients are then treated with a TCA of 80-90% during pregnancy and followed by electrocautery and excision during cesarean section. The results of 80-90% TCA treatment followed by electrocautery and excision were satisfactory, and there were no recurrences when the patient went for a follow-up. TCA is a substance that is caustic and can erode skin and mucous membranes. TCA works by coagulation of proteins which causes dryness of cells and tissues. TCA is safe for pregnant women. Combination of TCA 80-90% with electrocautery and excision, in this case, proved to be effective with no sign of recurrence. The combination of TCA therapy with electrocautery and excision has proven effective and safe for pregnant patients.


Condyloma acuminata; pregnant women; TCA; excision; electrocautery


  1. Eassa BI, Bakr AA. Intradermal injection of PPD as a novel approach of immunotherapy in anogenital warts in pregnant women. Dermatologic Therapy, 2011; 24: 137–43.
  2. Daili SF, Indriatmi W, Zubier F, Nilasari H.. Infeksi Menular Seksual, Pedoman Praktis Diagnosis dan Tatalaksana. Kementrian Kesehatan RI. 2015; 29-30.
  3. Schwartz DB, Greenberg MD, Daoud Y, Reid R. Genital condylomas in pregnancy: use of trichloroacetic acid and laser therapy. Am J Obstet Gynecol, 1988; 158: 1407-16.
  4. Rozmus-Warcholińska W, Loch T, Czuba B, Mazurek U, Mucha J. Genital warts associated with HPV infection during II and III trimester of pregnancy-a case report and analysis of treatment options., 2007; 78(11): 888-91.
  5. Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines. MMWR 2010; 59(No.RR-12): 70-3.
  6. Nath D, Kumar B, Sharma KV, Kaur I, Gupta R, Malhotra S. Comparison of podophyllin and trichloroacetic acid for the treatment of genital warts. IJDVL, 1990; 56(1): 22-4.
  7. Yenny S. W., Kondiloma Akuminata pada Wanita Hamil: Salah Satu Modalitas Terapi. Jurnal Kesehatan Andalas. 2013; 2(1)
  8. Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines. MMWR 2006; 55(No.RR-11): 62-6.
  9. Matsunaga J, Bergman A, Bhatta NN. Genital condylomata acuminata in pregnancy: effectiveness, safety and pregnancy outcome following cryotherapy. British Journal of Obstetrics and Ciynaecology, 1987; 94: 168-72
  10. Lacey CJN, Woodhall SC, Wikstrom A, Ross J. IUSTI: 2010 European Guideline for the Management of Anogenital Warts in Adults, 2010: 1-18.
  11. Scheinfeld N, Lehman DS. An evidence-based review of medical and surgical treatments of genital warts. Dermatology Online Journal 2006; 12 (3): 5.
  12. Akhavizadegan H. Electrocautery Resection, Shaving with a Scalpel, and Podophyllin: a Combination Therapy for Giant Condyloma Acuminatum., World J Mens Health., 2015: 39-41

Full Text: PDF

DOI: 10.30595/hmj.v4i3.10252


  • There are currently no refbacks.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

ISSN: 2620-567X