Pengaruh Penambahan Karboksimetil Selulosa (Cmc) Terhadap Tingkat Crosslinking dan Kuat Tarik Peo Hidrogel Film
DOI:
https://doi.org/10.30595/techno.v18i2.1964Abstract
Penggunaan hidrogel film pada bidang kesehatan dan pertanian berkembang dengan pesat, hal ini di karenakan karakteristik istimewa dari hidrogel yang mampu menyerap air dan mempertahankan kandungan air didalamnya sehingga memiliki sifat lembut serta dapat dipakai pada aplikasi medis. Hidrogel film yang dibuat menggunakan bahan dasar polietilene oksida memiliki kekuatan mekanik yang rendah. Untuk itu perlu dikembangkan hidrogel film yang memiliki karakteristik mekanik yang lebih baik dengan menambahkan karboksi metil selulosa (cmc) didalam larutan polietilen oksida.
Berbagai komposisi larutan cmc/peo (5%, 10%, 15% dan 20%) diradiasi dengan menggunakan sinar electron beam untuk mendapatkan jaringan network diantara polimer yang diradiasi. Kandungan cmc mempengaruhi berbagai karakteristik hidrogel film seperti fraksi gel, rasio swelling, sifat mekanik. Â
Hasil penelitian menunjukkan bahwa pada penambahan cmc sampai dengan 10%, semakin tinggi kandungan cmc, maka tingkat kroslinking, kuat Tarik dan persen pemanjangan juga semakin naik. Sebaliknya semakin tinggi kandungan cmc, maka rasio swelling justru akan semakin menurun.
References
Cartmell JV, Sturtevant WR, Valadez M, Wolf ML, Hydrogel wound dressing product. US Patent 5059424 (1991).
Rajendran S and Anand SC, Applications of medical textiles, in Development in Medical Textiles, vol 32, The Textile Institute, Manchester, pp 10-17 (2002).
Peppas NA and Scott JE, J Controll Release 18: 95-100 (1992).
Abdelrahman T and Newton H, Surgery 29: 491-495 (2011).
Haryanto, Kim S.C., Kim J.H., Kim J.O., Ku, S, Cho.H., Han D.H., Huh.P., Macromolecular Research 22: 131-138 (2014)
Yoshi F, Zhanshan Y, Isobe K, Shinozaki K, Makuuchi K. Electron beam crosslinked PEO and PEO/PVA hydrogel for wound dressing. Radiation Physic and Chemistry 1999;55:133-138.
Ikada Y, Mita T, Horii F, Sakurada I, Radiat Phys Chem 9: 633-645 (1977).
Paul, B. M.; James, M. M.; Helen, E. G.; Brian, E.G.; James, H.N.; Bradely, S.H. Fertil. Steril. 2004, l8, 1.
Jang SS, Goddard WA, Kalani MYS. Mechanical and transport properties of the poly(ethylene oxide)-poly(acrylic acid) double network from molecular dynamic simulations. J Phys Chem B 2007;111:1729-1737.
Yoshi F, Zhanshan Y, Isobe K, Shinozaki K, Makuuchi K. Electron beam crosslinked PEO and PEO/PVA hydrogel for wound dressing. Radiation Physic and Chemistry 1999;55:133-138.
Nayak S, Kundu S.C. Sericin-Carboxymethyl Cellulose Porous Matrices as Cellular Wound Dressing Material. Journal of Biomedical Materials Research A 2013;102:1928-1940.
Dunn R, Lyman MD, Edelman PG, Campbell PK. Evaluation of the SprayGel adhesion barrier in the rat cecum abrasion and rabbit uterine horn adhesion models. Fertil Steril 2001;75:411–416.
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