Scoping Review: Benefits of Zingiberaceae Family in Patients With Cancer

Kusuma Ayu Diah, Yunia Annisa, Yenni Bahar, Indrasto Histopaedianto

Abstract


Traditional medicine has begun to be widely used in the treatment and prevention of disease, which is supported by the increasing prevelance of chronic diseases and failure of treatment with modern medicine. Cancer as one of the chronic diseases that causes the most death in the world has begun to change treatment patterns using traditional medicines to minimize side effects that occur, one of which is the Zingiberaceae family. This study was conducted to determine the benefits of the Zingiberaceae family in cancer patients, by reviewing published articles. Articles are searched through the Google Scholar, Pubmed and Scopus databases contained in the Publish and Perish application. The results of this study obtained three Zingiberaceae plants in 13 article that had been clinically testes on cancer patients and met the inclusion exclusion criteria for this study. The three plants are: Zingiber officinale (ginger), Curcuma longa (turmeric), and Boesenbergia rotunda (intersection of keys). Zingiber officinale (ginger) is known to have benefits for cancer patient by reducing nausea and vomiting caused by chemotherapy, while Curcuma Longa (turmeric)and Boesenbergia rotunda (cucumber) are known to reduce the degree of oral mucositis due to radiotherapy.


Keywords


Zingiberaceae; Cancer; Clinical trial; Zingiber Officinale; Curcuma longa; Boesenbergia rotunda

References


Ferlay J, Ervik M, Lam F E al. International Agency for Research on Cancer 2020. Glob Cancer Obs Cancer Today [Internet]. 2020;419:1–2. Available from: https://gco.iarc.fr/today/data/factsheets/populations/900-world-fact-sheets.pdf

2. World Health Organization. Cancer Incident in Indonesia. Int Agency Res Cancer. 2020;858:1–2.

3. Dewi RS, Wahyuni, Pratiwi E, Muharni S. Penggunaan Obat Tradisional Oleh Masyarakat di Kelurahan Tuah Karya Kota Pekanbaru. J Penelit Farm Indones. 2019;8(1):41–5.

4. Effendi M. Pemanfaatan Sistem Pengobatan Tradisional (BATTRA) DI Puskesmas (Studi Deskriptif Mengenai Intensitas Kunjungan dan Efektifitas Sistem Pengobatan Tradisional (Battra) di Puskesmas Gundih Surabaya). 2013;

5. Siswanto S. Pengembangan Kesehatan Tradisional Indonesia: Konsep, Strategi dan Tantangan. J Penelit dan Pengemb Pelayanan Kesehat. 2018;01:17–31.

6. Yarom N, Hovan A, Bossi P, Ariyawardana A, Jensen SB, Gobbo M, et al. Systematic review of natural and miscellaneous agents, for the management of oral mucositis in cancer patients and clinical practice guidelines — part 2: honey, herbal compounds, saliva stimulants, probiotics, and miscellaneous agents. Support Care Cancer. 2020;28(5):2457–72.

7. Seay IF, Elim HI. The Observation of Fast, Long Term, and Stable Performance of Toxic Absorption in Herbal Blessing Product Based on Galoba Maluku (Zingiberaceae Fruits). Sci Nat. 2019;2(2):122–7.

8. Larsen. Gingers of peninsular malaysia and singapore. Kota Kinabalu: Natural History Publications (Borneo); 1999. 1–8 p.

9. Fiske JG, Lawrence GHM. Taxonomy of Vascular Plants. Vol. 79, Bulletin of the Torrey Botanical Club. New York: The Macmillan Company; 1952. 334 p.

10. Abdurrahman N. Kurkumin pada Curcuma longa sebagai Tatalaksana Alternatif Kanker. J Agromedicine [Internet]. 2019; Available from: http://juke.kedokteran.unila.ac.id/index.php/agro/article/view/2422

11. Lianah. Biodiversitas Zingiberaceae Mijen Kota Semarang [Internet]. Sleman: Deepublish; 2020. Available from: https://e-service.lipipress.lipi.go.id/press/catalog/download/256/227/602-1?inline=1

12. Munawaroh E. Upaya Konservasi Ex-Situ Suku Zingiberaceae dari Taman Nasional Bukit Barisan Selatan, di Kebun Raya Liwa, Lampung Barat, Lampung. Semin Nas Pendidik Biol dan Saintek. 2020;71–86.

13. Sinaga E, Suprihatin, Wiryanti I. Perbandingan Daya Sitotoksik Ekstrak Rimpang 3 Jenis Tumbuhan Zingiberaceae Terhadap Sel Kanker Mcf-7. J Farm Indones [Internet]. 2011;7(Vol 5, No 3 (2011)):125–33. Available from: http://www.jfionline.org/index.php/jurnal/article/view/47

14. Triyanti M. INVENTARISASI FAMILY ZINGIBERACEAE YANG BERPOTENSI SEBAGAI OBAT DI KABUPATEN MUSI RAWAS. Natl Conf Math Sci … [Internet]. 2019; Available from: http://proceeding.uim.ac.id/index.php/nacomse/article/view/343

15. Pratomo NA, Yunita E, Widyarini S, &, Anshory H. Efek Anti Angiogenesis Temu Kunci (Boesenbergia Pandurata, (Roxb.) Schlect) pada Membran Korio Alantois Embrio Ayam yang Diinduksi Basic Fibroblast Growth Factor (bFGF). Khazanah. 2014;6(2):35–45.

16. Arksey H, O’Malley L. Scoping studies: Towards a methodological framework. Int J Soc Res Methodol Theory Pract. 2005;8(1):19–32.

17. Levac D, Colquhoun H, O’Brien KK. Scoping studies: Advancing the methodology. Implement Sci. 2010;5(1):1–9.

18. Kikuzaki H, Nakatani N. Antioxidant effects of some ginger constituents. J Food Sci. 1993;58(6):1407–10.

19. Aryanta IW. Manfaat jahe untuk kesehatan. J Widya Kesehat. 2019;1(2):39–43.

20. Walstab J, Krueger D, Stark T, Hofmann T, Demir I., Ceyhan G., et al. Ginger and Its Pungent Constituents Non-Competitively Inhibit Activation of Human Recombinant and Native 5-HT3 Receptors of Enteric Neurons. Neurogastroenterol Motil. 2013;25(5):439–447.

21. Gibellini L, Bianchini E, De BS, Nasi M, Cossarizza, A, Pinti M. Natural Compounds Modulating Mitochondrial Functions. Evidence-Based Complement Altern Med. 2015;1–13.

22. Shailendiran D, Pawar N, Chanchal A, Pandey R., Bohidar H., Verma A. haracterization And Antimicrobial Activity of Nanocurcumin and Curcumin. Nanosci Technol Soc Implic. 2011;1–7.

23. Sandy PM, Susilawati Y. REVIEW ARTIKEL : MANFAAT EMPIRIS DAN AKTIVITAS FARMAKOLOGI JAHE MERAH ( Zingiber officinale Roscoe ), KUNYIT (Curcuma domestica Val.) DAN KENCUR (Kaempferia galanga L.). Farmaka. 2021;19.

24. Limsuwan S, Piyawan S, Voravuthikunchai. Bactericidal, Bacteriolytic, and Antibacterial Virulence Activities of Boesenbergia pandurata (Roxb) Schltr Extract against Streptococcus pyogenes. Trop J Pharm Res. 2013;12(6):1023–8.


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DOI: 10.30595/hmj.v7i1.23146

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ISSN: 2620-567X