Efektivitas Rebusan Daun Salam (Syzygium polyanthum) Terhadap Penurunan Kadar Asam Urat Dalam Darah Mencit Putih Jantan

Authors

  • Meiriza Djohar Sekolah Tinggi Ilmu Farmasi Riau, Jl. Kamboja Sp. Baru, Pekanbaru
  • Rovi Paramitha Akademi Analis Kesehatan Yayasan Fajar, Pekanbaru

Abstract

ABSTRAK Hiperurisemia adalah suatu keadaan yang ditandai dengan meningkatnya kadar asam urat dalam darah. Daun salam dipercaya mampu menurunkan kadar asam urat darah, karena memiliki kandungan flavonoid, tanin, dan minyak asiri 0,05% yang terdiri dari eugenol dan sitral sebagai diuretik (peluruh kencing) dan analgesik (penghilang nyeri). Penelitian ini bertujuan untuk mengetahui efektifitas rebusan daun salam terhadap penurunan kadar asam urat dalam darah mencit putih jantan. Penelitian ini merupakan penelitian eksperimental dengan desain Pre and Post Test Controlled Group Design. Sampel pada penelitian ini adalah 24 ekor mencit putih jantan, dibagi dalam 4 kelompok. Analisa statistik mengunakan program SPSS 17.0 for Windows. Uji ANOVA dan Post Hoc Test digunakan sebagai uji statistik untuk melihat perbedaan antara masing-masing kelompok dan uji T untuk melihat perbedaan sebelum dan sesudah pemberian rebusan daun salam. Hasil uji ANOVA menunjukkan hasil yang signifikan p=0,000 (p0,05). Dari hasil penelitian tersebut dapat disimpulkan bahwa ada perbedaan kadar asam urat pada kelompok sampel mencit putih jantan setelah pemberian rebusan daun salam. Kata kunci: asam urat, daun salam, mencit putih, uji anova. ABSTRACT Hyperuricemia is a condition characterized by increased levels of uric acid in the blood. Bay leaves is believed to be able to lower blood uric acid levels, because it contains flavonoids, tannins, and 0.05% essential oils consisting of eugenol and citral, and active as a diuretic and analgesic. This study aims to determine the effectiveness of the decoction of bay leaves to decrease uric acid blood level of white male mice. This research is an experimental research design with Pre and Post Test Controlled Group Design. Samples in this study were 24 male white mice divided into 4 groups. Statistical analysis using SPSS 17.0 for Windows. ANOVA and Post Hoc Test was used as a statistical test to analyze the difference between each group and the T test to analyze the difference before and after administration of decoction of bay leaves. Results of ANOVA showed significant results p=0.000 (p0.05). From the results, it can be concluded that there are differences in uric acid blood level of white male mice after administration of decoction of bay leaves. Key words: ANOVA test, bay leaf, gout, white mice.

References

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Published

2015-12-05

How to Cite

Djohar, M., & Paramitha, R. (2015). Efektivitas Rebusan Daun Salam (Syzygium polyanthum) Terhadap Penurunan Kadar Asam Urat Dalam Darah Mencit Putih Jantan. PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 12(2), 176–185. Retrieved from http://jurnalnasional.ump.ac.id/index.php/PHARMACY/article/view/329

Issue

Jurnal Pharmacy, Vol. 12 No. 02 Desember 2015

Section

PHARMACY

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