Kajian Aktivitas Antioksidan: Potensi Ekstrak Air Daun Kelor (Moringa oleifera Lam.) dan Secang (Caesalpinia sappan L.) sebagai Anti Hiperglikemia

Authors

  • Dhigna Luthfiyani Citra Pradana Fakultas Kedokteran UPN Veteran Jakarta
  • Eldiza Puji Rahmi Fakultas Kedokteran UPN Veteran Jakarta
  • Annisa Farida Muti Fakultas Kedokteran UPN Veteran Jakarta

DOI:

https://doi.org/10.30595/pharmacy.v17i2.7636

Keywords:

antioksidan, daun kelor, ekstrak air, IC50, kayu secang

Abstract

Ekstrak air daun kelor (Moringa oleifera Lam.) mengandung senyawa aktif flavonoid, fenol, dan tanin yang berperan sebagai antioksidan yang dapat mencegah hiperglikemia dan hiperlipidemia. Secang (Caesalpinia sappan L.) mengandung brazilin yang dapat menurunkan glukosa darah. Aktivitas antioksidan ekstrak air daun kelor dan kayu secang menjadi dasar uji in vivo, oleh karena itu tujuan penelitian ini untuk mengetahui IC50 ekstrak air daun kelor dan kayu secang yang memiliki potensi sebagai antihiperglikemia. Penelitian merupakan studi eksperimental. Perhitungan IC50 menggunakan metode spektrofotometri UV-Visibel dengan DPPH. IC50 ekstrak air daun kelor, kombinasi daun kelor dan kayu secang, dan kayu secang masing-masing sebesar 217,21; 71,89; dan 8,18 ppm. Daya antioksidan kuat dan sedang berpotensi menurunkan kadar glukosa darah melalui mekanisme pengurangan Reactive Oxygen Species (ROS).

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Published

2020-12-31

How to Cite

Pradana, D. L. C., Rahmi, E. P., & Muti, A. F. (2020). Kajian Aktivitas Antioksidan: Potensi Ekstrak Air Daun Kelor (Moringa oleifera Lam.) dan Secang (Caesalpinia sappan L.) sebagai Anti Hiperglikemia. PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia), 17(2), 352–359. https://doi.org/10.30595/pharmacy.v17i2.7636

Issue

Jurnal Pharmacy, Vol. 17 No. 02 Desember 2020

Section

PHARMACY

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