Topical Jatropha multifida L. ointment improves perineal wound healing in postpartum mothers: a randomized controlled trial

Authors

  • Fitria Candra Fera Postgraduate Program, Health Polytechnic of Semarang, Semarang, Central Java, Indonesia, Indonesia
  • Marsum Postgraduate Program, Health Polytechnic of Semarang, Semarang, Central Java, Indonesia, Indonesia
  • Sri Rahayu Midwifery Professional Education Study Program, Department of Midwifery, Health Polytechnic of Denpasar, Denpasar, Bali, Indonesia, Indonesia
Vol. 24 No. 1 (2026)
Original Article
March 26, 2026
April 8, 2026

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Background: Postpartum perineal wound care may lead to infection if not managed properly. Jatropha multifida L. contains various secondary metabolites that may accelerate wound healing; however, clinical evidence remains limited.

Objective: This study aimed to evaluate the effectiveness of Jatropha multifida L. extract ointment compared with standard clean and dry wound care in promoting perineal wound healing.

Methods: This was a true experimental study with a pre–posttest control group design. A total of 60 postpartum mothers with second-degree perineal lacerations were randomly assigned into three groups: control, 15% extract, and 20% extract. The interventions were applied twice daily for 7 days. Wound healing was assessed on days 3, 5, and 7 using the REEDA (Redness, Edema, Ecchymosis, Discharge, Approximation) score.

Results: The Friedman test showed a significant reduction in REEDA scores across all groups (p < 0.001). The greatest decrease was observed in the 15% concentration group (mean = 0.4). Cohen’s d indicated a very large effect size (d = 1.835).

Conclusions: Jatropha multifida L. extract ointment at a 15% concentration was effective in improving perineal wound healing in postpartum mothers.