Penggunaan Antibiotik pada Persalinan dengan Induksi: Studi di RSUD Majenang dan RSUD M. A. Sentot Patrol
DOI:
https://doi.org/10.30595/pharmacy.v21i1.21295Keywords:
Penggunaan Antibiotik, Induksi Persalinan, Akurasi Ketepatan, RSUD M. A. Sentot Patrol, RSUD MajenangAbstract
Penggunaan antibiotik yang tidak rasional akan meningkatkan kemungkinan resistensi bakteri terhadap antibiotik di masa depan. Antibiotik umumnya diresepkan untuk wanita selama persalinan, bahkan bagi mereka yang menjalani persalinan dengan induksi. Pemberian antibiotik selama persalinan dianjurkan jika ada risiko tinggi bayi tertular infeksi. Penelitian ini bertujuan untuk menilai ketepatan indikasi, pasien, obat, dosis dan cara pemberian antibiotik pada persalinan dengan induksi di RSUD Majenang dan RSUD M. A. Sentot Patrol. Penelitian ini dilakukan dengan menggunakan pendekatan observasional deskriptif non eksperimental. Data dikumpulkan secara retrospektif (Januari - Desember 2022). Analisis dilakukan dengan menggunakan Pedoman Penggunaan Antibiotik dan Pedoman Nasional Penanggulangan Komplikasi Kehamilan oleh Kementerian Kesehatan. Temuan disajikan dalam bentuk tabel dan persentase. Sebanyak 96 pasien di RSUD Majenang dan 71 pasien di RSUD M. A. Sentot memenuhi kriteria inklusi. Semua parameter yang terkait dengan indikasi, pasien, obat, dosis dan cara pemberian 100% akurat dalam mengevaluasi penggunaan antibiotik dalam induksi persalinan di RSUD Majenang. Sebaliknya, ketepatan indikasi dan pasien di RSUD M.A. Sentot Patrol sebesar 40,58%. Untuk ketepatan obat sebesar 0%, hanya dosis dan cara pemberian antibiotik yang 100% tepat di RSUD M. A. Sentot Patrol. Kesimpulannya, penggunaan antibiotik pada persalinan induksi di RSUD Majenang sudah memenuhi harapan, sedangkan di RSUD M. Patrol masih ada ruang untuk perbaikan.
References
Amanda et al., 2014. Drug Information Handbook, 23rd Edition. Lexi-Comp.
Andalas M, Maharani CR, Hendrawan ER, Florean MR, Zulfahmi Z. 2019. Premature rupture of membranes and its management. Kedokteran Syiah Kuala Journal, 19(3).
Food and Drugs Administration. 2017. Ciprofloxacin Use by Pregnant and Lactating Women. Accessed on 5 December from https://www.fda.gov/drugs/bioterrorism-and-drug-preparedness/ciprofloxacin-use-pregnant-and-lactating-women
Ivana Hartanto A, Ririel Kusumosih TA, Indrarto W. 2021. Pregnancy and childbirth outcomes in mothers with severe pre-eclampsia at Panti Wilasa Citarum Hospital, Semarang. Indonesian Journal of Obstetrics & Gynecology Science, 4(1), 20–27.
Illahi R, Pramestutie H, Susilaningtyas W. 2018. Cost-effectiveness analysis of cefotaxime, ceftriaxone, and levofloxacin in the treatment of typhoid fever: A study from Kanjuruhan Hospital, Malang, Indonesia. Value in Health, 21, S65.
Indramayu District Health Service. 2020. Profile of the Indramayu District Health Service in 2020. Accessed on 5 December from https://dinkes.indramayukab.go.id/wp-content/uploads/2021/09/Profil-Kesehatan-2020.pdf
Kusuma AM, Galistiani GF, Wijayanti DN, Umami M, Utaminingrum W. 2016. Quantitative evaluation of antibiotic use in caesarean section patients in regional hospitals throughout Banyumas Regency. Jurnal Farmasi Indonesia 8(1).
Maulidya NN, Yulia R, Herawati F. 2022. Literature review: Patterns of prophylaxic antibiotic use in patients with caesarea sectio delivery. Biomedika, 14(1), 33–45.
Maydea C. 2015. Midwifery Care for NY. P Mothers with Mild Pre-eclampsia at Wonosari Regional Hospital, Yogyakarta. Tesis. Yogyakarta: Sekolah Tinggi Ilmu Kesehatan Alma Ata
Ministry of Health, Indonesia. 2013. Maternal Health Services in Basic and Referral Health Facilities.
Ministry of Health, Indonesia. 2015. Wise and Rational Use of Antibiotics Reduces the Burden of Infectious Diseases. Accessed on 5 December from https//farmalkes.kemkes.go.id/2015/08/penggunaan-antibiotik-bijak-dan-rasional-kurangi-beban-penyakit-infeksi/
Ministry of Health, Indonesia. 2021. The Republic of Indonesia Minister of Health Regulation Number 28 of 2021 concerning Antibiotics Use Guidelines. Accessed on 5 December from https://yankes.kemkes.go.id/unduhan/fileunduhan_1658480966_921055.pdf
Ministry of Health, Indonesia. 2021. Indonesian Health Profile. Accessed on 5 December from https://www.kemkes.go.id/id/profil-kesehatan-indonesia-2021
Nastuti A. 2020. Maternal and Infant Mortality Rates in Cilacap Regency are Still High. Accessed on 5 December from https://cilacapkab.go.id/v3/angka-kematian-ibu-dan-bayi-di-kabupaten-cilacap-masih-tinggi/
Puruhita A, Lathifah N, Desilestia DS. 2016. Factors Associated with Failed Labor Induction. Skripsi. Kendari: Politeknik Kesehatan Kendari
Putri AA, Al Farisyi J, Saputra TH, 2022. Profile of antibiotic use in normal post-delivery patients at the Griya Sehat Friends of Mother Jember Maternity Home. urnal Farmasi dan Manajemen Kefarmasian, 1, 8–14.
Rasti SD, Rochmanti M, Primariawan RY. 2020. Cefotaxime vs ceftriaxone for the management of preterm premature rupture of membranes. The International Arabic Journal of Antimicrobial Agents, 10(1).
Reni R, Sunarsih. 2016. The effectiveness of vaginal administration of misoprostol with Intravenous oxytocin on the progress of labor in women giving birth indications at Asy-Syifaa Islamic Hospital Bandar Jaya in 2016. Jurnal Kebidanan Malahayati, 3.
Rosyada A, Rachmawati AD, Maisaroh DE. 2022. Appropriate Profile of Antibiotic Therapy in Patients with Premature Rupture of Amninos at Jemursari Islamic Hospital, Surabaya. Jurnal Ilmiah Mahaganesha, 1(2).
Sileshi A, Tenna A, Feyissa M, Shibeshi W. 2016. Evaluation of ceftriaxone utilization in medical and emergency wards of Tikur Anbessa specialized hospital: A prospective cross-sectional study. BMC Pharmacology and Toxicology, 17(1), 7.
Sudarto T. 2016. Risk of premature rupture of membranes in pregnant women with sexually transmitted infections. Jurnal Vokasi Kesehatan, 11(2), 126–131.
Trihapsari D, Agustina T, Lestari N, Raharja S. 2021. Relationship of mother's age and parities on the event of early premature rupture of membranes in PKU Muhammadiyah Surakarta Hospital. Alhamdic Conference Proceeding, 1, 136-145.
World Health Organization (WHO). 2022. WHO Recommendations on Induction of Labour, et or Beyond Term. Accessed on 5 December from https://www.who.int/publications/i/item/9789240052796
World Health Organization (WHO). 2023. Maternal Mortality. Accessed on 5 December from https://www.who.int/news-room/fact-sheets/detail/maternal-mortality
Wibowo MINA, Sugiri MP, Arrista B, Setiawan D. 2021. Off-label use of misoprostol in obstetrics-gynecology patients in district private hospitals, Banyumas. Jurnal Sains Farmasi & Klinis, 8(1), 9.
Yanuarini TA, Kristianti S, Sari ELA. 2022. Mother's characteristics in successful oxytocin drip labor induction. Jurnal Wiyata: Penelitian Sains Dan Kesehatan, 9(1), 1.
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