Quality Control Of Crude Drugs And Capsules Of Turmeric (Curcuma longa L.)
DOI:
https://doi.org/10.30595/pharmacy.v15i2.2811Keywords:
capsules, crude drugs, Curcuma longa L., quality control, standardization, turmericAbstract
Turmeric (Curcuma longa L.) is a medicinal plant commonly used in Thai Traditional Medicine (TTM), both in single use and formula. It has been known for its antioxidant activity and applied for management of many diseases. In this article, we reported some aspects of quality control of crude drugs and capsules of turmeric according to the standards set in Thai Herbal Pharmacopeia (THP). The results of our evaluations demonstrated that turmeric crude drugs met the criteria set in THP for microscopical identification, foreign matter (1.31%), loss on drying (6.89±0.174%), ethanol-soluble extractive (13.56%), water-soluble extractive (15.17%), and the profile of Thin Layer Chromatography (TLC) chromatogram. However, its volatile oil content (5.95%) was below the minimum value set in THP. The turmeric capsules met the criteria set in THP for loss on drying (8.64±0.093%), ethanol-soluble extractive (18.07%), water-soluble extractive (14.95%), and profile of TLC chromatogram.
References
Alam, F., Saqib, Q.N.U. 2015. Pharmacognostic study and development of quality control parameters for fruit, bark and leaf of Zanthoxylum armatum (Rutaceae). Ancient Science of Live, 34(3):147–155.
Alamgir, A.N.M. 2017. Herbal drugs: their collection, preservation, and preparation; evaluation, quality control, and standardization of herbal drugs. In: Rainsford, K.D. (Ed.). Therapeutic Use of Medicinal Plants and Their Extracts. Volume 1. Switzerland: Springer International Publishing, Cham.
Chusri, S., Settharaksa, S., Chokpaisarn, J., Limsuwan, S., Voravuthikunchai, S.P. 2013. Thai herbal formulas used for wound treatment: a study of their antibacterial potency, anti-inflammatory, antioxidant, and cytotoxicity effects. Journal of Alternative and Complementary Medicine, 19(7): 671–676.
Cimanga, K., Kambu, K., Tona, L., Apers, S., De Bruyne, T., Hermans, N., Totté, J., Pieters, L., Vlietinck, A.J. 2002. Correlation between chemical composition and antibacterial activity of essential oils of some aromatic medicinal plants growing in the Democratic Republic of Congo. Journal of Ethnopharmacology, 79(2):213–220.
Lim, T.K. 2016. Curcuma longa. In: Lim, T.K. (Ed.). Edible Medicinal and Non-Medicinal Plants. Volume 12 Modified Stems, Roots, Bulbs. Switzerland: Springer.
Meng, F.-C., Zhou, Y.-Q., Ren, D., Wang, R., Wang, C., Lin, L.-G., Zhang, X.-Q., Ye, W.-C., Zhang, Q.-W. 2018. Turmeric: a review of its chemical composition, quality control, bioactivity, and pharmaceutical application. In: Holban, A.M.B.T.-N. and A.F.A. and F.D. (Ed.). Handbook of Food Bioengineering. London: Academic Press.
Neamsuvan, O., Kama, A., Salaemae, A., Leesen, S., Waedueramae, N. 2015. A survey of herbal formulas for skin diseases from Thailand’s three southern border provinces. Journal of Herbal Medicine, 5(4):190–198.
Omosa, L.K., Midiwo, J.O., Kuete, V. 2017. Curcuma longa. In: Kuete, V. (Ed.). Medicinal Spices and Vegetables from Africa Therapeutic Potential Against Metabolic, Inflammatory, Infectious and Systemic Diseases. Dschang, Cameroon: Academic Press.
Poonthananiwatkul, B., Lim, R.H.M., Howard, R.L., Pibanpaknitee, P., Williamson, E.M. 2015. Traditional medicine use by cancer patients in Thailand. Journal of Ethnopharmacology, 168:100–107.
THP. 2016. Thai Herbal Pharmacopeia 2016. Bangkok: Department of Medical Sciences.
WHO. 2011. Quality Control Methods for Herbal Materials, World Health Organization. Geneva: World Health Organization.
Downloads
Published
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
