Formulasi, Evaluasi Sifat Fisik, dan Uji Efektivitas Tabir Surya Losion Ekstrak Buah Jamblang (Syzygium cumini (L.) Skeels)
DOI:
https://doi.org/10.30595/pharmacy.v17i1.9011Keywords:
jamblang, losion tabir surya, SPF, Syzygium cumini (L.) Skeels, uji sifat fisikAbstract
Angka kejadian kanker kulit yang dijumpai di Indonesia cukup tinggi sekitar 5,9-7,8%. Salah satu penyebabnya adalah paparan sinar UV berlebihan pada kulit. Dengan demikian diperlukan adanya suatu produk yang dapat melindungi kulit dari bahaya sinar UV. Pada penelitian terdahulu buah jamblang dilaporkan memiliki nilai faktor perlindungan terhadap matahari (sun protection factor/SPF) yaitu 2,278±0,25% yang berpotensi untuk dibuat sediaan tabir surya. Penelitian ini bertujuan untuk membuat formula losion ekstrak buah jamblang (Syzygium cumini (L.) Skeels) yang kemudian diuji karakteristik fisik dan efektivitas tabir surya dari produk tersebut. Buah jamblang kering dihaluskan dan diayak pada 40/60 mesh sehingga didapatkan serbuk simplisia dan dihitung rendemennya. Sebanyak 100 g serbuk diekstraksi dengan metode remaserasi dalam pelarut etanol 70% selama 3x24 jam dan ditambahkan secukupnya HCl 37% hingga pH 1. Maserat kemudian disaring dan dipekatkan dengan rotary evaporator sampai diperoleh ekstrak kental. Formulasi losion ekstrak buah jamblang dibuat dengan metode continental. Dilakukan pengujian terhadap sifat fisik losion meliputi organoleptis, homogenitas, viskositas, daya sebar, dan kemampuan tabir surya. Rendemen ekstrak buah jamblang sebesar 18,10%. Hasil pengamatan organoleptis menunjukkan warna ekstrak merah keunguan yang menunjukkan adanya antosianin pada lempeng KLT dengan hRf 16 dan berwarna mauve. Formula losion yang dihasilkan homogen dengan pH 6-7 dan viskositas 5460-4840 cP. Daya sebar dan daya lekat belum memenuhi persyaratan yaitu >7. Nilai SPF dari ekstrak buah jamblang menurun setelah dibuat sediaan losion.References
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