Karakter Mutu Simplisia dan Ekstrak Tumbuhan Antidiabetes Lokal dari Banyumas
DOI:
https://doi.org/10.30595/jrst.v6i2.15545Keywords:
Catharanthus roseus, Kadar Fenolik Total, Kadar Flavonoid Total, Melia azedarach, Muntingia calabura, Parameter MutuAbstract
Daun mindi (Melia azedarach L.), buah kersen (Muntingia calabura L.), serta daun dan bunga tapakdara (Catharanthus roseus (L.) G.Don) digunakan masyarakat Baturraden dan Sumbang (Banyumas) untuk pengobatan tradisional diabetes. Penelitian ini mengkarakterisasi beberapa parameter mutu simplisia dan ekstrak ketiga tumbuhan tersebut. Simplisia dibuat dari bahan tumbuhan yang dikumpulkan dari tiga desa di wilayah kecamata Baturraden dan Sumbang. Morfologi makroskopik dan mikroskopik, profil kromatografi lapis tipis (KLT), kadar fenolik total, dan kadar flavonoid total simplisia, serta kadar air, kadar abu total, dan kadar abu tidak larut asam ekstrak dianalisis dengan metode standar dalam Farmakope Herbal Indonesia (FHI) 2017. Karakter makroskopik, fragmen diagnostik, dan profil KLT dari simplisia hasil penelitian ini diusulkan untuk menjadi standar dalam memastikan kebenaran identitas simplisia. Kadar fenolik total dan kadar flavonoid total simplisia daun mindi, buah kersen, serta daun dan bunga tapakdara masing-masing sebesar 0,74±0,07 dan 0,99±0,31; 1,62±0,36 dan 1,39±0,11; dan 0,94±0,02 dan 1,98±0,04%. Nilai tersebut diusulkan sebagai standar untuk aspek kandungan masing-masing simplisia. Data kadar air, kadar abu total, dan kadar abu tidak larut asam diusulkan sebagai standar aspek kemurnian dari masing-masing ekstrak.
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